Dr Mitchell Lawrence is a Senior Research Fellow at Monash University with a part-time appointment at Peter Mac since 2017. His expertise includes the use of human preclinical models to study tumour biology, pathology, and novel therapies.

Dr Lawrence uses patient-derived xenografts (PDXs) and organoids from the Melbourne Urological Research Alliance (MURAL). These models represent the clinico-pathological and genomic spectrum of prostate cancer, from treatment-naïve primary tumors to castration-resistant metastases. For these multidisciplinary studies, Dr Lawrence works with a diverse team of collaborators, including urologists, oncologists, pathologists, bioinformaticians and patient advocates.

Dr Lawrence also collaborates with Associate Professor Kaylene Simpson and the team from the Victorian Centre for Functional Genomics to develop high-throughput 3D assays with prostate cancer cells.